Evaluation of cardiotoxicity and other adverse effects associated with concomitant administration of artemether/lumefantrine and atazanavir/ritonavir-based antiretroviral regimen in patients living with HIV

The interplay of artemether-lumefantrine (AL) and atazanavir-ritonavir (ATVr) with Cytochrome P (CYP) 3A4 isoenzyme and QTc-interval may spawn clinically significant drug interactions when administered concomitantly. Cardiotoxicity and other adverse effects associated with interaction between AL and...

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Bibliografische Detailangaben

Hauptverfasser:	Sikiru Olatunji Usman, Ibrahim Adekunle Oreagba, AbdulWasiu Busari, Akinwumi Akinyede, Ololade Adewumi, Michael Rotimi Kadri, Olayinka Hassan, Yinka Adeyemi Fashina, Esther Oluwatoyin Agbaje, Sulaimon Alani Akanmu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Springer 2022-05-01
Schriftenreihe:	Saudi Pharmaceutical Journal
Schlagworte:	Atazanavir-ritonavir Artemether-lumefantrine Cardiotoxicity LUTH
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S1319016422000512
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