Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation

Abstract Background Measurements of the amyloid-β (Aβ) 42/40 ratio in blood plasma may support the early diagnosis of Alzheimer’s disease and aid in the selection of suitable participants in clinical trials. Here, we compared the diagnostic performance of fully automated prototype plasma Aβ42/40 ass...

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Hlavní autoři:	Hans-W. Klafki, Jonathan Vogelgsang, Ekaterina Manuilova, Chris Bauer, Alexander Jethwa, Hermann Esselmann, Anke Jahn-Brodmann, Dirk Osterloh, Ingolf Lachmann, Benedict Breitling, Carolin Rauter, Niels Hansen, Caroline Bouter, Stefan Palme, Johannes Schuchhardt, Jens Wiltfang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2022-09-01
Edice:	Alzheimer’s Research & Therapy
Témata:	Alzheimer’s disease Biomarker assay Plasma Amyloid-β 42/40 Immunoprecipitation Pre-analytical sample workup
On-line přístup:	https://doi.org/10.1186/s13195-022-01071-y
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