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Comparison of the ability of exosomes and ectosomes derived from adipose-derived stromal cells to promote cartilage regeneration in a rat osteochondral defect model

Abstract Background Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) offer promising prospects for stimulating cartilage regeneration. The different formation mechanisms suggest that exosomes and ectosomes possess different biological functions. However, little attention ha...

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Principais autores: Tengjing Xu, Xinning Yu, Kaiwang Xu, Yunting Lin, Jiajie Wang, Zongyou Pan, Jinghua Fang, Siheng Wang, Zhuxing Zhou, Hongyun Song, Sunan Zhu, Xuesong Dai
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-01-01
Serier:Stem Cell Research & Therapy
Fag:
Cartilage regeneration
Mesenchymal stromal cells
Exosomes
Ectosomes
Macrophages
Online adgang:https://doi.org/10.1186/s13287-024-03632-4
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