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Minocycline modulates antigen-specific CTL activity through inactivation of mononuclear phagocytes in patients with HTLV-I associated neurologic disease

<p>Abstract</p> <p>Background</p> <p>The activation of mononuclear phagocytes (MPs), including monocytes, macrophages and dendritic cells, contributes to central nervous system inflammation in various neurological diseases. In HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), MPs...

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Principais autores: Enose-Akahata Yoshimi, Matsuura Eiji, Tanaka Yuetsu, Oh Unsong, Jacobson Steven
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2012-02-01
Series:Retrovirology
Assuntos:
HTLV-I
HAM/TSP
monocyte
CTL
minocycline
Acceso en liña:http://www.retrovirology.com/content/9/1/16
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