Obesity dysregulates the pulmonary antiviral immune response

Abstract Obesity is a well-recognized risk factor for severe influenza infections but the mechanisms underlying susceptibility are poorly understood. Here, we identify that obese individuals have deficient pulmonary antiviral immune responses in bronchoalveolar lavage cells but not in bronchial epit...

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Autors principals:	Mark Almond, Hugo A. Farne, Millie M. Jackson, Akhilesh Jha, Orestis Katsoulis, Oliver Pitts, Tanushree Tunstall, Eteri Regis, Jake Dunning, Adam J. Byrne, Patrick Mallia, Onn Min Kon, Ken A. Saunders, Karen D. Simpson, Robert J. Snelgrove, Peter J. M. Openshaw, Michael R. Edwards, Wendy S. Barclay, Liam M. Heaney, Sebastian L. Johnston, Aran Singanayagam
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2023-10-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-023-42432-x
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