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FUNCTIONAL IMPLICATIONS OF THE CLOCK 3111T/C SINGLE-NUCLEOTIDE POLYMORPHISM

Circadian rhythm disruptions are prominently associated with Bipolar Disorder (BD). Circadian rhythms are regulated by the molecular clock, a family of proteins that function together in a transcriptional-translational feedback loop. The CLOCK protein is a key transcription factor of this feedback l...

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Guardado en:
Autores principales: Angela Renee Ozburn, Kush ePurohit, Puja K Parekh, Gabrielle N Kaplan, Edgardo eFalcon, Shibani eMukherjee, Hannah M Cates, Colleen A McClung
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016-04-01
Colección:Frontiers in Psychiatry
Materias:
Bipolar Disorder
Gene Expression
cell culture
circadian
Single-nucleotide polymorphism
clock
Acceso en línea:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2016.00067/full
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