Computational modeling of interacting VEGF and soluble VEGF receptor concentration gradients

Experimental data indicates that soluble VEGF receptor 1 (sFlt-1) modulates the guidance cues provided to sprouting blood vessels by vascular endothelial growth factor-A (VEGF). To better delineate the role of sFlt-1 in VEGF signaling, we have developed an experimentally-based computational model....

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Bibliografske podrobnosti

Principais autores:	Yasmin L Hashambhoy, John C Chappell, Shayn M Peirce, Victoria L Bautch, Feilim eMac Gabhann
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2011-10-01
Serija:	Frontiers in Physiology
Teme:	Developmental Biology computational model mathematical model VEGF Angiogenesis Vascular Development
Online dostop:	http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00062/full
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