Targeting PI3K and AMPKα Signaling Alone or in Combination to Enhance Radiosensitivity of Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype and is characterized by poor survival. Radiotherapy plays an important role in treating TNBC. The purpose of this study was to determine whether inhibiting the AMP-activated protein kinase (AMPK) and phosphatidylinosit...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Jeremy Johnson, Zeta Chow, Dana Napier, Eun Lee, Heidi L. Weiss, B. Mark Evers, Piotr Rychahou
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2020-05-01
Schriftenreihe:	Cells
Schlagworte:	triple negative breast cancer radiation radiosensitivity AMPK PI3K
Online-Zugang:	https://www.mdpi.com/2073-4409/9/5/1253
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