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The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer

Using patient-derived organoids the authors show how a specialized polarity pathway protects our gut barrier from stress-induced collapse. Findings highlight both diagnostic and therapeutic potential of the pathway for treating gut barrier dysfunction in aging, cancer, and dysbiosis. The gut barrier...

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Autors principals: Pradipta Ghosh, Lee Swanson, Ibrahim M Sayed, Yash Mittal, Blaze B Lim, Stella-Rita Ibeawuchi, Marc Foretz, Benoit Viollet, Debashis Sahoo, Soumita Das
Format: Artigo
Idioma:Inglês
Publicat: Life Science Alliance LLC 2020-03-01
Col·lecció:Life Science Alliance
Accés en línia:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201900481
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