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Regulatory Effect and Mechanism of Tanshinone I on Cell Apoptosis in Steroid‐Induced Osteonecrosis of the Femoral Head

ABSTRACT Steroid‐induced osteonecrosis of the femoral head (SIONFH) is a debilitating orthopedic condition. This study investigated the mechanism of Tanshinone I (TsI) in SIONFH modulating apoptosis in SIONFH via the PI3K/AKT/mTOR pathway. A SIONFH rat model was treated with TsI and a PI3K activator...

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Sparad:
Huvudupphov: Qing Su, Jia Chen
Materialtyp: Artigo
Språk:Inglês
Utgiven: Wiley 2025-12-01
Serie:Kaohsiung Journal of Medical Sciences
Ämnen:
osteocytes
phosphatidylinositol 3‐kinase/AKT/mammalian target of rapamycin
phosphorylation
steroid‐induced osteonecrosis of the femoral head
Tanshinone I
Länkar:https://doi.org/10.1002/kjm2.70086
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