Regulation of thromboxane receptor signaling at multiple levels by oxidative stress-induced stabilization, relocation and enhanced responsiveness.

Thromboxane A(2) (TxA(2)) is a major, unstable arachidonic acid metabolite, and plays a key role in normal physiology and control of vascular tone. The human thromboxane receptor (TPβ), expressed in COS-7 cells, is located predominantly in the endoplasmic reticulum (ER). Brief hydrogen peroxide expo...

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Principais autores:	Stephen K Ball, Mark C Field, John R Tippins
格式:	Artigo
语言:	Inglês
出版:	Public Library of Science (PLoS) 2010-09-01
丛编:	PLoS ONE
在线阅读:	http://europepmc.org/articles/PMC2939892?pdf=render
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