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EPHA2 is associated with age-related cortical cataract in mice and humans.

Age-related cataract is a major cause of blindness worldwide, and cortical cataract is the second most prevalent type of age-related cataract. Although a significant fraction of age-related cataract is heritable, the genetic basis remains to be elucidated. We report that homozygous deletion of Epha2...

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Auteurs principaux: Gyungah Jun, Hong Guo, Barbara E K Klein, Ronald Klein, Jie Jin Wang, Paul Mitchell, Hui Miao, Kristine E Lee, Tripti Joshi, Matthias Buck, Preeti Chugha, David Bardenstein, Alison P Klein, Joan E Bailey-Wilson, Xiaohua Gong, Tim D Spector, Toby Andrew, Christopher J Hammond, Robert C Elston, Sudha K Iyengar, Bingcheng Wang
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2009-07-01
Collection:PLoS Genetics
Accès en ligne:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000584&type=printable
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