Key target genes related to anti-breast cancer activity of ATRA: A network pharmacology, molecular docking and experimental investigation

All-trans retinoic acid (ATRA) has promising activity against breast cancer. However, the exact mechanisms of ATRA's anticancer effects remain complex and not fully understood. In this study, a network pharmacology and molecular docking approach was applied to identify key target genes related to AT...

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Autori principali:	Hamed Manoochehri, Maryam Farrokhnia, Mohsen Sheykhhasan, Hanie Mahaki, Hamid Tanzadehpanah
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-07-01
Serie:	Heliyon
Soggetti:	All-trans-retinoic acid Breast neoplasia Drug-target prediction Network pharmacology Protein-protein interaction network
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2405844024103313
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