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Prevalence of fungal colonization among patients with psoriasis in difficult-to-treat areas: impact of apremilast on mycotic burden and clinical outcomes

IntroductionFungi, including Candida, may be a trigger or exacerbate psoriasis, especially in difficult to treat (DTT) areas, through the activation of IL-17/23 axis.MethodsIn this study, seventy patients with DDT psoriasis were enrolled to evaluate Candida species and/or other opportunistic fungi c...

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Autori principali: Elena Campione, Terenzio Cosio, Enrico Salvatore Pistoia, Fabio Artosi, Ruslana Gaeta Shumack, Cristiana Borselli, Antonia Rivieccio, Valerio Caputo, Marco Favaro, Roberto Sorge, Francesca Pica, Luca Bianchi, Roberta Gaziano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-12-01
Serie:Frontiers in Immunology
Soggetti:
apremilast
difficult-to-treat psoriasis areas
Candida species
fungal infections
cytokines
IL-17
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1508489/full
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