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Combination of targeted pharmacotherapy and immunotherapy with anti‐CD19 CAR NK cells in acute lymphoblastic leukemia

Abstract Anti‐CD19 CAR NK cells may provide a promising non‐HLA‐restricted immune cell product and have been clinically studied primarily on low‐grade B‐cell lymphoma patients. We used retroviral gene transfer to generate aCD19 CAR NK cells from the peripheral blood of healthy volunteers. We evaluat...

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Auteurs principaux: Hanna Kirchhoff, Caroline Schoenherr, Lisa Fleischer, Elizabeth K. Schweighart, Ruth Esser, Steven R. Talbot, Axel Schambach, Ulrike Koehl, Olaf Heidenreich, Matthias Eder, Michaela Scherr
Format: Artigo
Langue:Inglês
Publié: Wiley 2025-10-01
Collection:HemaSphere
Accès en ligne:https://doi.org/10.1002/hem3.70238
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