Association of NF-κB and AP-1 with MMP-9 Overexpression in 2-Chloroethanol Exposed Rat Astrocytes

Subacute poisoning of 1,2-dichloroethane (1,2-DCE) has become a serious occupational problem in China, and brain edema is its main pathological consequence, but little is known about the underlying mechanisms. As the metabolite of 1,2-DCE, 2-chloroethanol (2-CE) is more reactive, and might play an i...

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Auteurs principaux:	Tong Wang, Xiaoxia Jin, Yingjun Liao, Qi Sun, Chaohong Luo, Gaoyang Wang, Fenghong Zhao, Yaping Jin
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2018-08-01
Collection:	Cells
Sujets:	1,2-Dichloroethane poisoning 2-Chloroethanol matrix metalloproteinases-9 p38 MAPK signal pathway nuclear factor-κB activator protein-1
Accès en ligne:	http://www.mdpi.com/2073-4409/7/8/96
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