APE1/Ref‐1 knockdown in pancreatic ductal adenocarcinoma – characterizing gene expression changes and identifying novel pathways using single‐cell RNA sequencing

Apurinic/apyrimidinic endonuclease 1/redox factor‐1 (APE1/Ref‐1 or APE1) is a multifunctional protein that regulates numerous transcription factors associated with cancer‐related pathways. Because APE1 is essential for cell viability, generation of APE1‐knockout cell lines and determining a comprehe...

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Detalhes bibliográficos

Principais autores:	Fenil Shah, Emery Goossens, Nadia M. Atallah, Michelle Grimard, Mark R. Kelley, Melissa L. Fishel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2017-12-01
coleção:	Molecular Oncology
Assuntos:	APE1 pancreatic ductal adenocarcinoma Ref‐1 RNA sequencing single cell
Acesso em linha:	https://doi.org/10.1002/1878-0261.12138
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