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Genotyping of apolipoprotein A-IV by digestion of amplified DNA with restriction endonuclease Fnu4HI: use of a tailored primer to abolish additional recognition sites during the gene amplification

Apolipoprotein A-IV (apoA-IV) is involved in the metabolism of chylomicrons and high density lipoproteins. It displays genetic polymorphism due to two co-dominant alleles apoA-IV1 and apoA-IV2. The mutation that causes the polymorphism is a G to T substitution in the third base of codon 360 in the a...

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Autore principale: H Tenkanen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 1991-03-01
Serie:Journal of Lipid Research
Accesso online:http://www.sciencedirect.com/science/article/pii/S0022227520420784
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