Lysine myristoylation mediates long-term potentiation via membrane enrichment of synaptic plasticity effectors

Abstract Synaptic plasticity underlying long-term memory is associated with the generation of saturated free fatty acids (sFFAs) –particularly myristic acid– from membrane phospholipids by the phospholipase A1 isoform DDHD2. However, the mechanism through which myristic acid contributes to synaptic...

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Detalles Bibliográficos

Autores principales:	Benjamin Matthews, Sevannah A Steeves, Isaac O Akefe, Noorya Yasmin Ahmed, Rachel S Gormal, Nathalie Dehorter, Tristan P Wallis, Frédéric A Meunier
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Springer Nature 2025-06-01
Colección:	The EMBO Journal
Materias:	DDHD2 N-Myristoyl Transferase Myristic Acid Lysine Myristoylation Long-Term Potentiation
Acceso en línea:	https://doi.org/10.1038/s44318-025-00484-3
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