Probiotics mitigate non-antibiotic drug-induced dysbiosis via protein homology-driven competitive binding

Abstract While the impact of non-antibiotic drugs on gut bacteria is well-known, their mechanisms of action remain poorly characterized, and effective mitigation strategies for drug-induced dysbiosis are still limited. Here, we screened bacteria-derived drug-target protein homologs (BDTPHs) mapped t...

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Váldodahkkit:	Shuo Feng, Shu-xin Zhou, Zi-lin Si, Yu-min Cai, Yi-fan Huangfu, Yi-jia Hou, Zi-tong Wang, Qi Liu, Hong-xi Liu, Li-juan Zhai, Tao He, Mao Gu, Gong-hui Tan, Ao-bo Zhang, Jun-ling Zhao, Tao Xu, Yan Ling, Ying-jian Hou, Xiao Zheng, Jing Li, Xing-zhen Lao
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Nature Portfolio 2026-05-01
Ráidu:	Nature Communications
Liŋkkat:	https://doi.org/10.1038/s41467-026-72592-5
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