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12‐HETE is an Endogenous Modulator of BLT2 Triggering Vascular Degeneration, Dissection, and Rupture

Abstract Thoracic aortic dissection (TAD), a life‐threatening vascular emergency requiring urgent pharmacological intervention, prompted investigation into arachidonic acid metabolites based on their established roles in inflammation and vascular homeostasis. Through comprehensive plasma metabolomic...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yuyu Li, Jiaqi Yu, Weiyao Chen, Xue Wang, Xin Tan, Jing Cui, Yihao Wang, Xuan Xu, Rui Lin, Zhengkai Wang, Wenxi Jiang, Yongliang Zhong, Jie Du, Yuan Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2026-01-01
Schriftenreihe:Advanced Science
Schlagworte:
aortic dissection
inflammation
macrophage
smooth muscle cells
Online-Zugang:https://doi.org/10.1002/advs.202515897
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