TLR-Agonist Mediated Enhancement of Antibody-Dependent Effector Functions as Strategy For an HIV-1 Cure

BackgroundThe current treatment for HIV-1 is based on blocking various stages in the viral replication cycle using combination antiretroviral therapy (ART). Even though ART effectively controls the infection, it is not curative, and patients must therefore continue treatment life-long.AimHere we rev...

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Principais autores:	Caroline Thue Hvilsom, Ole Schmeltz Søgaard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-09-01
Colecção:	Frontiers in Immunology
Assuntos:	toll-like receptor agonists broadly neutralizing antibodies HIV-1 cure effector mechanisms ADCC HIV reservoir
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.704617/full
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