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Mutations inside rifampicin-resistance determining region of rpoB gene associated with rifampicin-resistance in Mycobacterium tuberculosis

Background: Rifampicin (RIF) plays a pivotal role in the treatment of tuberculosis due to its bactericidal effects. Because the action of RIF is on rpoB gene encoding RNA polymerase β subunit, 95% of RIF resistant mutations are present in rpoB gene. The majority of the mutations in rpoB gene are fou...

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Xehetasun bibliografikoak
Egile Nagusiak: Myo T. Zaw, Nor A. Emran, Zaw Lin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018-09-01
Saila:Journal of Infection and Public Health
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S1876034118300418
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