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Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape.

<h4>Background</h4>Antigen-specific CTL responses are thought to play a central role in containment of HIV-1 infection, but no consistent correlation has been found between the magnitude and/or breadth of response and viral load changes during disease progression.<h4>Methods and findings</h4>We unde...

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Principais autores: Annika C Karlsson, Astrid K N Iversen, Joan M Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J McMichael, Miles P Davenport, Frederick M Hecht, Douglas F Nixon
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2007-02-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000225&type=printable
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