When PIP2 Meets p53: Nuclear Phosphoinositide Signaling in the DNA Damage Response

The mechanisms that maintain genome stability are critical for preventing tumor progression. In the past decades, many strategies were developed for cancer treatment to disrupt the DNA repair machinery or alter repair pathway selection. Evidence indicates that alterations in nuclear phosphoinositide...

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Principais autores:	Yu-Hsiu Wang, Michael P. Sheetz
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-05-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	p53 DNA repair DNA damage response (DDR) nuclear phosphoinositide signaling repair pathway choice stress response
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2022.903994/full
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