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Targeting EphA2 in Bladder Cancer Using a Novel Antibody-Directed Nanotherapeutic

Ephrin receptor A2 (EphA2) is a member of the Ephrin/Eph receptor cell-to-cell signaling family of molecules, and it plays a key role in cell proliferation, differentiation, and migration. EphA2 is overexpressed in a broad range of cancers, and its expression is in many cases associated with poor pr...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Walid Kamoun, Elden Swindell, Christine Pien, Lia Luus, Jason Cain, Minh Pham, Irawati Kandela, Zhaohua Richard Huang, Suresh K. Tipparaju, Alexander Koshkaryev, Vasileios Askoxylakis, Dmitri B. Kirpotin, Troy Bloom, Mari Mino-Kenudson, James D. Marks, Alena Zalutskaya, Wiam Bshara, Carl Morrison, Daryl C. Drummond
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-10-01
Schriftenreihe:Pharmaceutics
Schlagworte:
bladder cancer
EphA2
antibody directed nanotherapeutic
liposomes
immunoliposomes
nanocarrier
Online-Zugang:https://www.mdpi.com/1999-4923/12/10/996
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