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Polycomb enables primitive endoderm lineage priming in embryonic stem cells

Mouse embryonic stem cells (ESCs), like the blastocyst from which they are derived, contain precursors of the epiblast (Epi) and primitive endoderm (PrEn) lineages. While transient in vivo, these precursor populations readily interconvert in vitro. We show that altered transcription is the driver of...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Robert S Illingworth, Jurriaan J Hölzenspies, Fabian V Roske, Wendy A Bickmore, Joshua M Brickman
Hōputu: Artigo
Reo:Inglês
I whakaputaina: eLife Sciences Publications Ltd 2016-10-01
Rangatū:eLife
Ngā marau:
Urunga tuihono:https://elifesciences.org/articles/14926
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