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Cyclodextran prevents Porphyromonas gulae and Porphyromonas gingivalis induced halitosis and cytokine secretion via direct inhibition of biofilm formation

Periodontal disease (PD) is an inflammatory condition affecting the supporting structures of teeth, initiated by bacterial biofilm formation. Porphyromonas gulae (P. gulae) and P. gingivalis are key pathogens in canine and human PD, respectively, producing biofilms, volatile sulfur compounds, and pr...

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Principais autores: Megu Toyooka, Mao Kaneki, Chiharu Ohira, Yasuyuki Nakamura, Mio Yamamoto, Tomoki Fukuyama
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-12-01
Serier:Frontiers in Oral Health
Fag:
cyclodextran
periodontal disease
porphyromonas gulae
porphyromonas gingivalis
biofilm
Online adgang:https://www.frontiersin.org/articles/10.3389/froh.2025.1713668/full
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