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Taipan Natriuretic Peptides Are Potent and Selective Agonists for the Natriuretic Peptide Receptor A

Cardiovascular ailments are a major cause of mortality where over 1.3 billion people suffer from hypertension leading to heart-disease related deaths. Snake venoms possess a broad repertoire of natriuretic peptides with therapeutic potential for treating hypertension, congestive heart failure, and r...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Simone Vink, Kalyana Bharati Akondi, Jean Jin, Kim Poth, Allan M. Torres, Philip W. Kuchel, Sandra L. Burke, Geoffrey A. Head, Paul F. Alewood
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-03-01
Schriftenreihe:Molecules
Schlagworte:
taipan natriuretic peptide
peptide synthesis
NMR structure
peptide stability
TNP pharmacology
Online-Zugang:https://www.mdpi.com/1420-3049/28/7/3063
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