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Design and Synthesis of Novel Candidate CK1δ Proteolysis Targeting Chimeras (PROTACs)

The dysregulation of CK1 isoforms is linked to various types of diseases, including neurodegeneration and different types of neoplasia such as colon, pancreatic, breast, and ovarian cancer. For CK1 isoforms, a plethora of effective small molecule inhibitors are available. However, only a few degrade...

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Detaylı Bibliyografya
Asıl Yazarlar: Malte Arnold, Temi Thompson, Lorraine Glennie, Mattes Hollnagel, Gopal Sapkota, Christian Peifer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2025-11-01
Seri Bilgileri:Molecules
Konular:
Online Erişim:https://www.mdpi.com/1420-3049/30/22/4452
Etiketler: Etiketle
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