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In Vitro Generation of BK polyomavirus-specific T cells for adoptive cell therapy in refractory cystitis hemorrhagic patients after hematopoietic stem cell transplantation

Abstract Introduction BKPyV associated hemorrhagic cystitis (BKPyV-HC) is a major and prevalent outcome of hematopoietic stem cell transplantation (HSCT) with no standard treatment option. Adoptive T cell therapy (ACT) against transplant-associated viruses has shown promising potential. We sought to...

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Principais autores: Maryam Mohammadi Najafabadi, Masoud Soleimani, Mohammad Ahmadvand, Mina Soufi Zomorrod, Seied Asadollah Mousavi
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-06-01
coleção:BMC Immunology
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Acesso em linha:https://doi.org/10.1186/s12865-022-00497-1
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