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Convenient screening of the reproductive toxicity of favipiravir and antiviral drugs in Caenorhabditis elegans

Reproductive toxicity is one of the major concerns in drug development. Thus, we have developed its screening system using Caenorhabditis elegans, which has a life cycle of three days and similar coding genes as humans. Antiviral nucleoside analogs used for acute infections are known to cause reprod...

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Bibliografiske detaljer
Principais autores: Kimiyasu Shiraki, Mizuki Mishima, Noriaki Sato, Yasuo Imoto, Kiyoji Nishiwaki
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-08-01
Serier:Heliyon
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S240584402411362X
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