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Substituting Inosine for Guanosine in DNA: Structural and Dynamic Consequences

Inosine differs from the guanosine nucleoside only by the absence of the N2 amino group. Both nucleosides also have similar electrostatic potentials. Therefore, substituting I for G has been used to probe various properties of nucleic acids and to facilitate the interpretation of binding studies. In...

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Autori principali: Zachary E. Ferris, Qiushi Li, Markus W. Germann
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publishing 2019-05-01
Serie:Natural Product Communications
Accesso online:https://doi.org/10.1177/1934578X19850032
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