Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8⁺ T Cells

ABSTRACT Curing HIV-1 infection will require elimination of persistent cellular reservoirs that harbor latent virus in the face of combination antiretroviral therapy (cART). Proposed immunotherapeutic strategies to cure HIV-1 infection include enhancing lysis of these infected cells by cytotoxic T l...

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Detalhes bibliográficos

Principais autores:	Kellie N. Smith, Robbie B. Mailliard, Paolo A. Piazza, Will Fischer, Bette T. Korber, Ronald J. Fecek, Deena Ratner, Phalguni Gupta, James I. Mullins, Charles R. Rinaldo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2016-07-01
Colecção:	mBio
Acesso em linha:	https://journals.asm.org/doi/10.1128/mBio.00473-16
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