Comprehensive analysis of mutations associated with rifampicin- and isoniazid-resistant tuberculosis in a high-burden setting

ABSTRACT Background: In this study, we aimed to describe the mutations associated with first-line drug resistance in Mycobacterium tuberculosis complex (MTBC) isolates from São Paulo, Brazil, between 2019 and 2021. Methods: Mutations in the coding regions of rpoB and katG genes and in the promot...

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Autors principals:	Rosângela Siqueira de Oliveira, Angela Pires Brandão, Fabiane Maria de Almeida Ferreira, Sonia Maria da Costa, Vera Lucia Maria da Silva, Lucilaine Ferrazoli, Erica Chimara, Juliana Maira Watanabe Pinhata
Format:	Artigo
Idioma:	Inglês
Publicat:	Sociedade Brasileira de Medicina Tropical (SBMT) 2025-09-01
Col·lecció:	Revista da Sociedade Brasileira de Medicina Tropical
Matèries:	Drug susceptibility test Gene sequencing GenoType MTBDRplus Multidrug-resistant tuberculosis Mycobacterium tuberculosis
Accés en línia:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822025000100413&lng=en&tlng=en
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