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Post-translational weapons of microbial warfare: how bacterial effectors hijack host cell death and xenophagy

Abstract The intricate interplay between pathogenic bacteria and host cellular processes represents a dynamic molecular battlefield during infection. Mammalian hosts employ two critical cell-autonomous defense mechanisms, regulated cell death (RCD) and xenophagy, to combat invading pathogens. RCD el...

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Main Authors: Kun Meng, Liuliu Shi, Xianglan Fang, Jin Yang, Yan Ding, Zheng Cao, Shan Li
Format: Artigo
Language:Inglês
Published: BMC 2025-10-01
Series:Cell Communication and Signaling
Subjects:
Pathogenic bacteria
Post-translational modifications (PTMs)
Regulated cell death (RCD)
Xenophagy
Host–pathogen interactions
Online Access:https://doi.org/10.1186/s12964-025-02470-y
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