regQTLs: Single nucleotide polymorphisms that modulate microRNA regulation of gene expression in tumors.
Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with trait diversity and disease susceptibility, yet their functional properties often remain unclear. It has been hypothesized that SNPs in microRNA binding sites may disrupt gene regulation by...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2018-12-01
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| Serie: | PLoS Genetics |
| Accesso online: | https://doi.org/10.1371/journal.pgen.1007837 |
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