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Association of the Transmembrane Serine Protease-2 (TMPRSS2) Polymorphisms with COVID-19

SARS-CoV-2 uses the ACE2 receptor and the cellular protease TMPRSS2 for entry into target cells. The present study aimed to establish if the TMPRSS2 polymorphisms are associated with COVID-19 disease. The study included 609 patients with COVID-19 confirmed by RT-PCR test and 291 individuals negative...

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Principais autores: Rosalinda Posadas-Sánchez, José Manuel Fragoso, Fausto Sánchez-Muñoz, Gustavo Rojas-Velasco, Julian Ramírez-Bello, Alberto López-Reyes, Laura E. Martínez-Gómez, Carlos Sierra-Fernández, Tatiana Rodríguez-Reyna, Nora Elemi Regino-Zamarripa, Gustavo Ramírez-Martínez, Joaquín Zuñiga-Ramos, Gilberto Vargas-Alarcón
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-09-01
coleção:Viruses
Assuntos:
COVID-19 disease
genetic susceptibility
polymorphisms
SARS-CoV-2 infection
transmembrane serine protease-2 (TMPRSS2)
Acesso em linha:https://www.mdpi.com/1999-4915/14/9/1976
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