Differentially Expressed Potassium Channels Are Associated with Function of Human Effector Memory CD8+ T Cells

The voltage-gated potassium channel, Kv1.3, and the Ca2+-activated potassium channel, KCa3.1, regulate membrane potentials in T cells, thereby controlling T cell activation and cytokine production. However, little is known about the expression and function of potassium channels in human effector mem...

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Autori principali:	Ji Hyun Sim, Kyung Soo Kim, Hyoungjun Park, Kyung-Jin Kim, Haiyue Lin, Tae-Joo Kim, Hyun Mu Shin, Gwanghun Kim, Dong-Sup Lee, Chan-Wook Park, Dong Hun Lee, Insoo Kang, Sung Joon Kim, Chung-Hyun Cho, Junsang Doh, Hang-Rae Kim
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2017-07-01
Serie:	Frontiers in Immunology
Soggetti:	human effector memory CD8+ T cells interleukin-7Rαlow effector memory CD8+ T cells calcium-activated potassium channel KCa3.1 voltage-gated potassium channel Kv1.3 T-cell motility transendothelial migration
Accesso online:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00859/full
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