Regulatory role of isthmin-1 in glucose and lipid metabolism and its clinical implications
Isthmin-1 (ISM1), a novel adipokine, regulates glucose and lipid metabolism with a tissue-specific manner. In skeletal muscle and adipose tissue, ISM1 activates the insulin-independent mTORC2/PI3K/AKT signaling pathway, promoting GLUT4 translocation to the membrane, enhancing glucose uptake, and imp...
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| Glavni autor: | |
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| Format: | Artigo |
| Jezik: | Chinês |
| Izdano: |
Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2026-03-01
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| Serija: | Jichu yixue yu linchuang |
| Teme: | |
| Online pristup: | https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2026-46-3-445.pdf |
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