RUNX1 colludes with NOTCH1 to reprogram chromatin in T cell acute lymphoblastic leukemia

Summary: Runt-related transcription factor 1 (RUNX1) is oncogenic in diverse types of leukemia and epithelial cancers where its expression is associated with poor prognosis. Current models suggest that RUNX1 cooperates with other oncogenic factors (e.g., NOTCH1, TAL1) to drive the expression of prot...

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Principais autores:	Rashedul Islam, Catherine E. Jenkins, Qi Cao, Jasper Wong, Misha Bilenky, Annaïck Carles, Michelle Moksa, Andrew P. Weng, Martin Hirst
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-06-01
coleção:	iScience
Assuntos:	Molecular biology Cancer systems biology Cancer
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2589004223008726
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