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Mitochondrial Reactive Oxygen Species Mediate Activation of TRPV1 and Calcium Entry Following Peripheral Sensory Axotomy

Axons that are physically separated from their soma activate a series of signaling events that results in axonal self-destruction. A critical element of this signaling pathway is an intra-axonal calcium rise that occurs just prior to axonal fragmentation. Previous studies have shown that preventing...

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Hlavní autoři: Bradley Kievit, Aaron D. Johnstone, Julien Gibon, Philip A. Barker
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-03-01
Edice:Frontiers in Molecular Neuroscience
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fnmol.2022.852181/full
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