Environmental Toxin Biliatresone-Induced Biliary Atresia-like Abnormal Cilia and Bile Duct Cell Development of Human Liver Organoids

Biliary atresia (BA) is a poorly understood and devastating obstructive bile duct disease of newborns. Biliatresone, a plant toxin, causes BA-like syndrome in some animals, but its relevance in humans is unknown. To validate the hypothesis that biliatresone exposure is a plausible BA disease mechani...

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Ngā kaituhi matua:	Yue Hai-Bing, Menon Sudheer Sivasankaran, Babu Rosana Ottakandathil, Wu Zhong-Luan, So Man-Ting, Chung (Patrick) Ho-Yu, Wong (Kenneth) Kak-Yuen, Tam (Paul) Kwong-Hang, Lui (Vincent) Chi-Hang
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2024-03-01
Rangatū:	Toxins
Ngā marau:	biliatresone biliary atresia organoids
Urunga tuihono:	https://www.mdpi.com/2072-6651/16/3/144
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!