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Leishmanicidal and immunomodulatory activities of the formononetin (a natural isoflavone) against Leishmania tropica

Abstract Objective This work aimed to examine the leishmanicidal, cellular mechanisms and cytotoxicity effects of formononetin (FMN), a natural isoflavone, against Leishmania tropica. We used the MTT assay to determine the leishmanicidal effects of FMN against promastigotes and its cytotoxicity effe...

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Principais autores: Hossein Mahmoudvand, Amal Khudair Khalaf, Pouya Zareh Rajabi, Nooshin Karbasian, Javad Ghasemian Yadegari
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-06-01
Serier:BMC Research Notes
Fag:
Leishmaniasis
Promastigote
Amastigote
Nitric oxide
Infectivity
Online adgang:https://doi.org/10.1186/s13104-023-06403-1
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