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Glucocorticoid-dependence and independence of the circadian liver transcriptome

Abstract The liver, a key metabolic organ, shows clear day-night variation in gene and protein expression, and in metabolic pathway activity. Liver cells possess molecular circadian clocks, but systemic factors are critical contributors to the circadian rhythmicity of liver gene expression. Glucocor...

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Principais autores: Robert J. Maidstone, A. Louise Hunter, Mudassar Iqbal, Nicola Begley, Matthew Baxter, Andrew S. I. Loudon, Magnus Rattray, David W. Ray
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2026-02-01
Series:npj Biological Timing and Sleep
Acceso en liña:https://doi.org/10.1038/s44323-025-00068-8
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