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Treatment of therapy-related acute myeloid leukemia and acute myeloid leukemia with myelodysplasia-related changes: a comparative analysis of higher-dose intensive 7+3 induction chemotherapy <i>versus</i> liposomal cytarabine and daunorubicin

Therapy-related acute myeloid leukemia (t-AML) and AML with myelodysplasia-related changes (AML-MRC) are associated with poor outcomes. The liposomal formulation of cytarabine and daunorubicin (CPX-351) improved complete remission (CR) and CR with incomplete hematologic recovery (CRi) rates and ove...

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Auteurs principaux: Dimitrios Kotsos, Patrycja Gradowska, Sjoerd J.F. Hermans, Thomas Pabst, Johan Maertens, Markus Manz, Dimitri A. Breems, Bjorn T. Gertsen, Soren Lehmann, Bart J. Biemond, Berna H. Beverloo, Peter J.M. Valk, Jeroen J.W.M. Janssen, Gert Ossenkoppele, Bob Löwenberg, Gerwin Huls, Marc H.G.P. Raaijmakers, Jurjen Versluis.
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2026-03-01
Collection:Haematologica
Accès en ligne:https://haematologica.org/article/view/13423
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