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Virtual screening of marine coumarins and xanthenes identifies novel acid-suppressive leads targeting histamine H₂ receptor and gastric proton pump

Marine natural products represent a diverse collection of structurally distinct metabolites, many of which have untapped therapeutic potential. This study screened 161 marine-derived coumarin and xanthene compounds for their binding affinity to the histamine H₂ receptor and the gastric H⁺/K⁺-ATPase...

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Autori principali: Amar Osmanović, Mirsada Salihović, Amila Mehmedović, Amila Turalić, Elma Veljović, Mirha Pazalja, Simone Carradori, Selma Špirtović-Halilović
Natura: Artigo
Lingua:Inglês
Pubblicazione: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2026-01-01
Serie:Biomolecules & Biomedicine
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Accesso online:https://www.bjbms.org/ojs/index.php/bjbms/article/view/13660
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