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BH3-mimetics: recent developments in cancer therapy

Abstract The hopeful outcomes from 30 years of research in BH3-mimetics have indeed served a number of solid paradigms for targeting intermediates from the apoptosis pathway in a variety of diseased states. Not only have such rational approaches in drug design yielded several key therapeutics, such...

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Autori principali: Paul A. Townsend, Maria V. Kozhevnikova, Olivier N. F. Cexus, Andrey A. Zamyatnin, Surinder M. Soond
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2021-11-01
Serie:Journal of Experimental & Clinical Cancer Research
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Accesso online:https://doi.org/10.1186/s13046-021-02157-5
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