Sensitive RP-HPLC method with fluorimetric detection for concurrent quantification of emtricitabine, Daclatasvir and Ledipasvir in human urine

Abstract Co-infection with hepatitis C virus (HCV) in human immunodeficiency virus (HIV) patients is common and has a poor prognosis leading to many complications. The anti-HIV drug emtricitabine (FTC) is co-administered with two direct acting anti-HCV drugs; daclatasvir (DAC) and ledipasvir (LDV)....

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Principais autores:	Aya A. Youssef, N. Magdy, Lobna A. Hussein, A. M. El-Kosasy
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2025-07-01
Series:	Scientific Reports
Assuntos:	Emtricitabine Daclatasvir Ledipasvir Bioanalytical validation HIV/HCV co-infection
Acceso en liña:	https://doi.org/10.1038/s41598-025-07401-y
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