Asymmetric Mannich reaction of aromatic imines with malonates in the presence of multifunctional catalysts
Various multifunctional enantiomerically pure organocatalysts were synthesized and screened in asymmetric Mannich reaction. The reaction of aromatic imines with malonates in the presence of amino acid-derived catalysts gave Mannich adducts in very high enantiomeric purities (up to 98% ee). It is pro...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Beilstein-Institut
2026-01-01
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| Col·lecció: | Beilstein Journal of Organic Chemistry |
| Matèries: | |
| Accés en línia: | https://doi.org/10.3762/bjoc.22.8 |
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